CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications

BACKGROUND: Variation in the CYP2D6 gene may affect response to opioids in both poor and ultrarapid metabolizers, but data demonstrating such associations have been mixed, and the impact of variants on toxicity-related symptoms (e.g., nausea) is unclear. Therefore, we examined the association betwee...

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Dades bibliogràfiques
Publicat a:Pharmgenomics Pers Med
Autors principals: St Sauver, Jennifer L, Olson, Janet E, Roger, Veronique L, Nicholson, Wayne T, Black, John L, Takahashi, Paul Y, Caraballo, Pedro J, Bell, Elizabeth J, Jacobson, Debra J, Larson, Nicholas B, Bielinski, Suzette J
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533497/
https://ncbi.nlm.nih.gov/pubmed/28769582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S136341
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