CYP2D6 phenotypes are associated with adverse outcomes related to opioid medications

BACKGROUND: Variation in the CYP2D6 gene may affect response to opioids in both poor and ultrarapid metabolizers, but data demonstrating such associations have been mixed, and the impact of variants on toxicity-related symptoms (e.g., nausea) is unclear. Therefore, we examined the association betwee...

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Bibliografiske detaljer
Udgivet i:Pharmgenomics Pers Med
Main Authors: St Sauver, Jennifer L, Olson, Janet E, Roger, Veronique L, Nicholson, Wayne T, Black, John L, Takahashi, Paul Y, Caraballo, Pedro J, Bell, Elizabeth J, Jacobson, Debra J, Larson, Nicholas B, Bielinski, Suzette J
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533497/
https://ncbi.nlm.nih.gov/pubmed/28769582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S136341
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