Sex Differences in Associations Between CYP2D6 Phenotypes and Response to Opioid Analgesics

BACKGROUND: Several small studies have previously investigated associations between the cytochrome P450 2D6 (CYP2D6) metabolism and response to opioids. We used a large sample of patients to study associations between CYP2D6 phenotypes and estimated CYP2D6 enzymatic activity scores with pain control...

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Bibliografiske detaljer
Udgivet i:Pharmgenomics Pers Med
Main Authors: Lopes, Guilherme S, Bielinski, Suzette J, Moyer, Ann M, Black III, John Logan, Jacobson, Debra J, Jiang, Ruoxiang, Larson, Nicholas B, St Sauver, Jennifer L
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081062/
https://ncbi.nlm.nih.gov/pubmed/32214840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S239222
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