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Impact of Pharmacogenomic Information on Values of Care and Quality of Life Associated with Codeine and Tramadol-Related Adverse Drug Events

OBJECTIVE: To assess the potential impact of Pharmacogenomic (PGx) variation in cytochrome P450 2D6 (CYP2D6) enzyme function, using loss in quality-adjusted life years (QALYs) associated with treatment problems, and the willingness to pay to avoid treatment problems from patients’ and payers’ perspe...

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Detalhes bibliográficos
Publicado no:Mayo Clin Proc Innov Qual Outcomes
Main Authors: Zhu, Ye, Lopes, Guilherme S., Bielinski, Suzette J., Borah, Bijan J., Larson, Nicholas B., Moyer, Ann M., Olson, Janet E., Wang, Liewei, Weinshilboum, Richard, St. Sauver, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930862/
https://ncbi.nlm.nih.gov/pubmed/33718782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mayocpiqo.2020.08.009
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