The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

BACKGROUND: Doxorubicin (DOX) is a very effective anticancer medication that is commonly used to treat hematological malignancies and solid tumors. Nevertheless, DOX is known to have cardiotoxic effects that may lead to cardiac dysfunction and failure. In experimental studies, female animals have be...

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Detalles Bibliográficos
Publicado en:Cardiooncology
Main Authors: Zordoky, Beshay N., Radin, M. Judith, Heller, Lois, Tobias, Anthony, Matise, Ilze, Apple, Fred S., McCune, Sylvia A., Sharkey, Leslie C.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533296/
https://ncbi.nlm.nih.gov/pubmed/28758028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40959-016-0013-3
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