The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

BACKGROUND: Doxorubicin (DOX) is a very effective anticancer medication that is commonly used to treat hematological malignancies and solid tumors. Nevertheless, DOX is known to have cardiotoxic effects that may lead to cardiac dysfunction and failure. In experimental studies, female animals have be...

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Bibliografiske detaljer
Udgivet i:Cardiooncology
Main Authors: Zordoky, Beshay N., Radin, M. Judith, Heller, Lois, Tobias, Anthony, Matise, Ilze, Apple, Fred S., McCune, Sylvia A., Sharkey, Leslie C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533296/
https://ncbi.nlm.nih.gov/pubmed/28758028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40959-016-0013-3
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