The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

BACKGROUND: Doxorubicin (DOX) is a very effective anticancer medication that is commonly used to treat hematological malignancies and solid tumors. Nevertheless, DOX is known to have cardiotoxic effects that may lead to cardiac dysfunction and failure. In experimental studies, female animals have be...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cardiooncology
Päätekijät: Zordoky, Beshay N., Radin, M. Judith, Heller, Lois, Tobias, Anthony, Matise, Ilze, Apple, Fred S., McCune, Sylvia A., Sharkey, Leslie C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533296/
https://ncbi.nlm.nih.gov/pubmed/28758028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40959-016-0013-3
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