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DNA twisting flexibility and the formation of sharply looped protein–DNA complexes

Gene-regulatory complexes often require that pairs of DNA-bound proteins interact by looping-out short (often ≈100-bp) stretches of DNA. The loops can vary in detailed length and sequence and, thus, in total helical twist, which radically alters their geometry. How this variability is accommodated s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cloutier, T. E., Widom, J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15718281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409059102
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