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DNA looping by Ku and the DNA-dependent protein kinase

The DNA-dependent protein kinase (DNA-PK) is required for DNA double-strand break (DSB) repair and immunoglobulin gene rearrangement and may play a role in the regulation of transcription. The DNA-PK holoenzyme is composed of three polypeptide subunits: the DNA binding Ku70/86 heterodimer and an ≈46...

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Main Authors: Cary, Robert B., Peterson, Scott R., Wang, Jinting, Bear, David G., Bradbury, E. Morton, Chen, David J.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC20711/
https://ncbi.nlm.nih.gov/pubmed/9113978
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