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Productive and Nonproductive Complexes of Ku and DNA-Dependent Protein Kinase at DNA Termini

DNA-dependent protein kinase (DNA-PK) is the only eukaryotic protein kinase known to be specifically activated by double-stranded DNA (dsDNA) termini, accounting for its importance in repair of dsDNA breaks and its role in physiologic processes involving dsDNA breaks, such as V(D)J recombination. In...

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Udgivet i:Mol Cell Biol
Principais autores: West, Robert B., Yaneva, Mariana, Lieber, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109177/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5908
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