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Productive and Nonproductive Complexes of Ku and DNA-Dependent Protein Kinase at DNA Termini

DNA-dependent protein kinase (DNA-PK) is the only eukaryotic protein kinase known to be specifically activated by double-stranded DNA (dsDNA) termini, accounting for its importance in repair of dsDNA breaks and its role in physiologic processes involving dsDNA breaks, such as V(D)J recombination. In...

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Detalhes bibliográficos
Main Authors: West, Robert B., Yaneva, Mariana, Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109177/
https://ncbi.nlm.nih.gov/pubmed/9742108
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