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DNA twisting flexibility and the formation of sharply looped protein–DNA complexes
Gene-regulatory complexes often require that pairs of DNA-bound proteins interact by looping-out short (often ≈100-bp) stretches of DNA. The loops can vary in detailed length and sequence and, thus, in total helical twist, which radically alters their geometry. How this variability is accommodated s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553319/ https://ncbi.nlm.nih.gov/pubmed/15718281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409059102 |
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