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DNA twisting flexibility and the formation of sharply looped protein–DNA complexes
Gene-regulatory complexes often require that pairs of DNA-bound proteins interact by looping-out short (often ≈100-bp) stretches of DNA. The loops can vary in detailed length and sequence and, thus, in total helical twist, which radically alters their geometry. How this variability is accommodated s...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553319/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15718281/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409059102 |
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