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Sizing clinical trials when comparing bivariate time-to-event outcomes
Clinical trials with multiple primary time-to-event outcomes are common. Use of multiple endpoints creates challenges in the evaluation of power and the calculation of sample size during trial design particularly for time-to-event outcomes. We present methods for calculating the power and sample siz...
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| Publicat a: | Stat Med |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533151/ https://ncbi.nlm.nih.gov/pubmed/28120524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7225 |
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