A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O(6)-alkylguanine-DNA alkyltransferase and endonuclease V activities

A recently discovered DNA repair protein of 303 aa from the archaeal organism Ferroplasma acidarmanus was studied. This protein (AGTendoV) consists of a fusion of the C-terminal active site domain of O(6)-alkylguanine-DNA alkyltransferase (AGT) with an endonuclease V domain. The AGTendoV recombinant...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kanugula, Sreenivas, Pauly, Gary T., Moschel, Robert C., Pegg, Anthony E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553313/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15731349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408719102
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