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The CD4 molecule on CD8(+) T lymphocytes directly enhances the immune response to viral and cellular antigens
CD8(+) T lymphocytes play a major role in cellular-mediated immune responses to foreign antigen. We have previously demonstrated that costimulation of purified human CD8(+) T cells induces de novo expression of the CD4 molecule and that ligation of CD4 on this cell type modulates CD8(+) T cell activ...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553300/ https://ncbi.nlm.nih.gov/pubmed/15731353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406603102 |
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