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Costimulation of Naive CD8(+) Lymphocytes Induces CD4 Expression and Allows Human Immunodeficiency Virus Type 1 Infection

Human immunodeficiency virus type 1 (HIV-1) infection requires cell surface expression of CD4. Costimulation of CD8(+)/CD4(−) T lymphocytes by anti-CD3 and anti-CD28 antibodies or by allogeneic dendritic cells induced expression of CD4 and rendered these CD8 cells susceptible to HIV-1 infection. Nai...

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Detalles Bibliográficos
Main Authors: Kitchen, Scott G., Korin, Yael D., Roth, Michael D., Landay, Alan, Zack, Jerome A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC110322/
https://ncbi.nlm.nih.gov/pubmed/9765450
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