Costimulation of Naive CD8(+) Lymphocytes Induces CD4 Expression and Allows Human Immunodeficiency Virus Type 1 Infection

Human immunodeficiency virus type 1 (HIV-1) infection requires cell surface expression of CD4. Costimulation of CD8(+)/CD4(−) T lymphocytes by anti-CD3 and anti-CD28 antibodies or by allogeneic dendritic cells induced expression of CD4 and rendered these CD8 cells susceptible to HIV-1 infection. Nai...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kitchen, Scott G., Korin, Yael D., Roth, Michael D., Landay, Alan, Zack, Jerome A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.9054-9060.1998
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