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Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of intracellul...

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Publicado en:Mol Biol Cell
Main Authors: Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M., Cunniff, Brian
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://ncbi.nlm.nih.gov/pubmed/28615318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0741
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