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Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of intracellul...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M., Cunniff, Brian
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://ncbi.nlm.nih.gov/pubmed/28615318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0741
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