Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of intracellul...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Cell
Autori principali: Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M., Cunniff, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2017
Soggetti:
Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://ncbi.nlm.nih.gov/pubmed/28615318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0741
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