Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration

It has long been postulated, although never directly demonstrated, that mitochondria are strategically positioned in the cytoplasm to meet local requirements for energy production. Here we show that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of intracellul...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Schuler, Max-Hinderk, Lewandowska, Agnieszka, Caprio, Giuseppe Di, Skillern, Wesley, Upadhyayula, Srigokul, Kirchhausen, Tom, Shaw, Janet M., Cunniff, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531732/
https://ncbi.nlm.nih.gov/pubmed/28615318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0741
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