Sirt3-dependent deacetylation of SOD2 plays a protective role against oxidative stress in oocytes from diabetic mice

Maternal diabetes has been demonstrated to adversely affect oocyte quality in mouse oocytes. However, the potential molecular mechanisms are poorly understood. Here, we established a type I diabetic mouse model and detected the increased reactive oxygen species (ROS) levels and decreased Sirt3 expre...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Liu, Xiaohui, Zhang, Liang, Wang, Pan, Li, Xiaoyan, Qiu, Danhong, Li, Ling, Zhang, Jiaqi, Hou, Xiaojing, Han, Longsen, Ge, Juan, Li, Mo, Gu, Ling, Wang, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531630/
https://ncbi.nlm.nih.gov/pubmed/28662362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1320004
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