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Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Although antigen cross-presentation in dendritic cells (DCs) is critical to the initiation of most cytotoxic immune responses, the intracellular mechanisms and traffic pathways involved are still unclear. One of the most critical steps in this process, the export of internalized antigen to the cytos...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Grotzke, Jeff E., Kozik, Patrycja, Morel, Jean-David, Impens, Francis, Pietrosemoli, Natalia, Cresswell, Peter, Amigorena, Sebastian, Demangel, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530691/
https://ncbi.nlm.nih.gov/pubmed/28679634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705242114
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