Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies

The analysis of genome-wide association studies (GWAS) benefits from the investigation of biologically meaningful gene sets, such as gene-interaction networks (pathways). We propose an extension to a successful kernel-based pathway analysis approach by integrating kernel functions into a powerful al...

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Bibliografiske detaljer
Udgivet i:Comput Math Methods Med
Main Authors: Friedrichs, Stefanie, Manitz, Juliane, Burger, Patricia, Amos, Christopher I., Risch, Angela, Chang-Claude, Jenny, Wichmann, Heinz-Erich, Kneib, Thomas, Bickeböller, Heike, Hofner, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530424/
https://ncbi.nlm.nih.gov/pubmed/28785300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6742763
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