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Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data

We used our extension of the kernel score test to family data to analyze real and simulated baseline systolic blood pressure in extended pedigrees. We compared the power for different kernels and for different weightings of genetic markers. Moreover, we compared the power of rare and common markers...

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Detalhes bibliográficos
Publicado no:BMC Proc
Main Authors: Malzahn, Dörthe, Friedrichs, Stefanie, Bickeböller, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133495/
https://ncbi.nlm.nih.gov/pubmed/27980648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0042-9
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