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A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies

Biological pathways provide rich information and biological context on the genetic causes of complex diseases. The logistic kernel machine test integrates prior knowledge on pathways in order to analyze data from genome-wide association studies (GWAS). Here, the kernel converts genomic information o...

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Detalhes bibliográficos
Main Authors: Freytag, Saskia, Manitz, Juliane, Schlather, Martin, Kneib, Thomas, Amos, Christopher I., Risch, Angela, Chang-Claude, Jenny, Heinrich, Joachim, Bickeböller, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026009/
https://ncbi.nlm.nih.gov/pubmed/24434848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357567
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