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A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies

Biological pathways provide rich information and biological context on the genetic causes of complex diseases. The logistic kernel machine test integrates prior knowledge on pathways in order to analyze data from genome-wide association studies (GWAS). Here, the kernel converts genomic information o...

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Hlavní autoři: Freytag, Saskia, Manitz, Juliane, Schlather, Martin, Kneib, Thomas, Amos, Christopher I., Risch, Angela, Chang-Claude, Jenny, Heinrich, Joachim, Bickeböller, Heike
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026009/
https://ncbi.nlm.nih.gov/pubmed/24434848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357567
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