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Empirical Hierarchical Bayes Approach to Gene-Environment Interactions: Development and Application to Genome-Wide Association Studies of Lung Cancer in TRICL

The analysis of gene-environment (GxE) interactions remains one of the greatest challenges in the post-genome-wide-association-studies (GWAS) era. Recent methods constitute a compromise between the robust but underpowered case-control and powerful case-only methods. Inferences of the latter are bias...

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Detalhes bibliográficos
Main Authors: Sohns, Melanie, Viktorova, Elena, Amos, Christopher I., Brennan, Paul, Fehringer, Gord, Gaborieau, Valerie, Han, Younghun, Heinrich, Joachim, Chang-Claude, Jenny, Hung, Rayjean J., Müller-Nurasyid, Martina, Risch, Angela, Thomas, Duncan, Bickeböller, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082246/
https://ncbi.nlm.nih.gov/pubmed/23893921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21741
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