Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype

The present report describes a unique infantile acute lymphoblastic leukemia (ALL) case with cryptic mixed-lineage leukemia (MLL) rearrangements with 11q23 chromosomal translocation. MLL break-apart signals were identified by fluorescence in situ hybridization, and transcriptome sequencing revealed...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Hiwatari, Mitsuteru, Seki, Masafumi, Akahoshi, Shogo, Yoshida, Kenichi, Miyano, Satoru, Shiraishi, Yuichi, Tanaka, Hiroko, Chiba, Kenichi, Ogawa, Seishi, Takita, Junko
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530220/
https://ncbi.nlm.nih.gov/pubmed/28781666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6430
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