α2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts

We investigated the mechanisms by which protein kinase C (PKC) regulates the expression of the α2(I) collagen gene in normal dermal fibroblasts. Reduction of PKC-α activity by treatment with Gö697-6 or by overexpression of a dominant negative (DN) mutant form decreased α2(I) collagen gene expression...

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Bibliographic Details
Main Authors: Jinnin, Masatoshi, Ihn, Hironobu, Yamane, Kenichi, Mimura, Yoshihiro, Asano, Yoshihide, Tamaki, Kunihiko
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC552962/
https://ncbi.nlm.nih.gov/pubmed/15741186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki275
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