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Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1

In this study, we clarified the molecular mechanism(s) underlying the regulation of matrix metalloproteinase (MMP)-1 gene by hepatocyte growth factor (HGF) in cultured human dermal fibroblasts. HGF induced MMP-1 protein as well as mRNA at a transcriptional level via extracellular signal-regulated ki...

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Autors principals: Jinnin, Masatoshi, Ihn, Hironobu, Mimura, Yoshihiro, Asano, Yoshihide, Yamane, Kenichi, Tamaki, Kunihiko
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156961/
https://ncbi.nlm.nih.gov/pubmed/15972796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki648
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