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Uric acid protects against secondary damage after spinal cord injury

Peroxynitrite contributes to the pathogenesis of various neurodegenerative disorders through multiple mechanisms and is thought to mediate secondary neuronal cell death after spinal cord injury (SCI). Here we establish that physiologically relevant levels of uric acid (UA), a selective inhibitor of...

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Detalhes bibliográficos
Main Authors: Scott, Gwen S., Cuzzocrea, Salvatore, Genovese, Tiziana, Koprowski, Hilary, Hooper, D. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC552934/
https://ncbi.nlm.nih.gov/pubmed/15728348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500307102
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