Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors

Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases. Serum UA levels are inversely associated with the incidence of MS in humans because MS patients have low se...

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Detalhes bibliográficos
Main Authors: Scott, Gwen S., Spitsin, Sergei V., Kean, Rhonda B., Mikheeva, Tatiana, Koprowski, Hilary, Hooper, D. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC138606/
https://ncbi.nlm.nih.gov/pubmed/12451183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212645999
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