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Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors
Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases. Serum UA levels are inversely associated with the incidence of MS in humans because MS patients have low se...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138606/ https://ncbi.nlm.nih.gov/pubmed/12451183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212645999 |
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