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Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors

Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases. Serum UA levels are inversely associated with the incidence of MS in humans because MS patients have low se...

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Detaylı Bibliyografya
Asıl Yazarlar: Scott, Gwen S., Spitsin, Sergei V., Kean, Rhonda B., Mikheeva, Tatiana, Koprowski, Hilary, Hooper, D. Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC138606/
https://ncbi.nlm.nih.gov/pubmed/12451183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212645999
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