Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors

Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases. Serum UA levels are inversely associated with the incidence of MS in humans because MS patients have low se...

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Bibliographische Detailangaben
Hauptverfasser: Scott, Gwen S., Spitsin, Sergei V., Kean, Rhonda B., Mikheeva, Tatiana, Koprowski, Hilary, Hooper, D. Craig
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC138606/
https://ncbi.nlm.nih.gov/pubmed/12451183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212645999
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