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The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

BACKGROUND: Emerging data implicate nicotinamide phosphoribosyl transferase (NAMPT) in the pathogenesis of cancer and inflammation. NAMPT inhibitors have proven beneficial in inflammatory animal models of arthritis and endotoxic shock as well as in autoimmune encephalitis. Given the role of inflamma...

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Bibliografiset tiedot
Päätekijät: Esposito, Emanuela, Impellizzeri, Daniela, Mazzon, Emanuela, Fakhfouri, Gohar, Rahimian, Reza, Travelli, Cristina, Tron, Gian Cesare, Genazzani, Armando A, Cuzzocrea, Salvatore
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353188/
https://ncbi.nlm.nih.gov/pubmed/22490786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-66
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