A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

Treating pancreatic cancer is extremely challenging due to multiple factors, including chemoresistance and poor disease prognosis. Chemoresistance can be explained by: the presence of a dense stromal barrier leading to a lower vascularized condition, therefore limiting drug delivery; the huge intra-...

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Pubblicato in:Oncotarget
Autori principali: Barraud, Marine, Garnier, Jonathan, Loncle, Celine, Gayet, Odile, Lequeue, Charlotte, Vasseur, Sophie, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Maignan, Aurélie, Moutardier, Vincent, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Ouaissi, Mehdi, Secq, Veronique, Poizat, Flora, Guibert, Nicolas, Iovanna, Juan, Dusetti, Nelson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288221/
https://ncbi.nlm.nih.gov/pubmed/27462772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10776
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