A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

Treating pancreatic cancer is extremely challenging due to multiple factors, including chemoresistance and poor disease prognosis. Chemoresistance can be explained by: the presence of a dense stromal barrier leading to a lower vascularized condition, therefore limiting drug delivery; the huge intra-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Barraud, Marine, Garnier, Jonathan, Loncle, Celine, Gayet, Odile, Lequeue, Charlotte, Vasseur, Sophie, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Maignan, Aurélie, Moutardier, Vincent, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Ouaissi, Mehdi, Secq, Veronique, Poizat, Flora, Guibert, Nicolas, Iovanna, Juan, Dusetti, Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288221/
https://ncbi.nlm.nih.gov/pubmed/27462772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10776
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