A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

Treating pancreatic cancer is extremely challenging due to multiple factors, including chemoresistance and poor disease prognosis. Chemoresistance can be explained by: the presence of a dense stromal barrier leading to a lower vascularized condition, therefore limiting drug delivery; the huge intra-...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Barraud, Marine, Garnier, Jonathan, Loncle, Celine, Gayet, Odile, Lequeue, Charlotte, Vasseur, Sophie, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Maignan, Aurélie, Moutardier, Vincent, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Ouaissi, Mehdi, Secq, Veronique, Poizat, Flora, Guibert, Nicolas, Iovanna, Juan, Dusetti, Nelson
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288221/
https://ncbi.nlm.nih.gov/pubmed/27462772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10776
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