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A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

Treating pancreatic cancer is extremely challenging due to multiple factors, including chemoresistance and poor disease prognosis. Chemoresistance can be explained by: the presence of a dense stromal barrier leading to a lower vascularized condition, therefore limiting drug delivery; the huge intra-...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Barraud, Marine, Garnier, Jonathan, Loncle, Celine, Gayet, Odile, Lequeue, Charlotte, Vasseur, Sophie, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Maignan, Aurélie, Moutardier, Vincent, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Ouaissi, Mehdi, Secq, Veronique, Poizat, Flora, Guibert, Nicolas, Iovanna, Juan, Dusetti, Nelson
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288221/
https://ncbi.nlm.nih.gov/pubmed/27462772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10776
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