The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

BACKGROUND: Emerging data implicate nicotinamide phosphoribosyl transferase (NAMPT) in the pathogenesis of cancer and inflammation. NAMPT inhibitors have proven beneficial in inflammatory animal models of arthritis and endotoxic shock as well as in autoimmune encephalitis. Given the role of inflamma...

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Библиографические подробности
Главные авторы: Esposito, Emanuela, Impellizzeri, Daniela, Mazzon, Emanuela, Fakhfouri, Gohar, Rahimian, Reza, Travelli, Cristina, Tron, Gian Cesare, Genazzani, Armando A, Cuzzocrea, Salvatore
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353188/
https://ncbi.nlm.nih.gov/pubmed/22490786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-66
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