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The Democratization of Gene Editing: Insights from site-specific cleavage and double-strand break repair

DNA double-strand breaks (DSBs) are dangerous lesions that if not properly repaired can lead to genomic change or cell death. Organisms have developed several pathways and have many factors devoted to repairing DSBs, which broadly occur by homologous recombination that relies on an identical or homo...

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書目詳細資料
發表在:DNA Repair (Amst)
Main Authors: Jasin, Maria, Haber, James E.
格式: Artigo
語言:Inglês
出版: 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529214/
https://ncbi.nlm.nih.gov/pubmed/27261202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.001
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