Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio‐resistance in breast cancer

Radiation‐induced DNA damage activates the DNA damage response (DDR). DDR up‐regulation may predict radio‐resistance and increase the risk of early local recurrence despite radiotherapy in early stage breast cancers. In 1755 early stage breast cancers, DDR signalling [ATM, ATR, total Ckh1, Chk1 phos...

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Publicado no:Mol Oncol
Main Authors: Alsubhi, Nouf, Middleton, Fiona, Abdel-Fatah, Tarek M.A., Stephens, Peter, Doherty, Rachel, Arora, Arvind, Moseley, Paul M., Chan, Stephen Y.T., Aleskandarany, Mohammed A., Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Martin, Stewart G., Curtin, Nicola J., Madhusudan, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528957/
https://ncbi.nlm.nih.gov/pubmed/26459098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.09.009
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