Topoisomerase‐1 and ‐2A gene copy numbers are elevated in mismatch repair‐proficient colorectal cancers

INTRODUCTION: Topoisomerase 1 (TOP1) and 2A (TOP2A) are potential predictive biomarkers for irinotecan and anthracycline treatment, respectively, in colorectal cancer (CRC), and we have recently reported a high frequency of gene gain of the TOP1 and TOP2A genes in CRC. Furthermore, Mismatch Repair (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Oncol
Päätekijät: Sønderstrup, Ida Marie Heeholm, Nygård, Sune Boris, Poulsen, Tim Svenstrup, Linnemann, Dorte, Stenvang, Jan, Nielsen, Hans Jørgen, Bartek, Jiri, Brünner, Nils, Nørgaard, Peter, Riis, Lene
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2015
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528751/
https://ncbi.nlm.nih.gov/pubmed/25777966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.02.009
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia