Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

PURPOSE: A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient pr...

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Publicado en:Mol Oncol
Main Authors: Rømer, Maria Unni, Nygård, Sune Boris, Christensen, Ib Jarle, Nielsen, Signe Lykke, Nielsen, Kirsten Vang, Müller, Sven, Smith, David Hersi, Vainer, Ben, Nielsen, Hans Jørgen, Brünner, Nils
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2012
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528401/
https://ncbi.nlm.nih.gov/pubmed/23110915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.09.001
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