DNA polymerase β deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts

Short arm of chromosome 8 is a hot spot for chromosomal breaks, losses and amplifications in breast cancer. Although such genetic changes may have phenotypic consequences, the identity of candidate gene(s) remains to be clearly defined. Pol β gene is localized to chromosome 8p12‐p11 and encodes a ke...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Abdel-Fatah, Tarek M.A., Russell, Roslin, Agarwal, Devika, Moseley, Paul, Abayomi, Michael Ayotunde, Perry, Christina, Albarakati, Nada, Ball, Graham, Chan, Stephen, Caldas, Carlos, Ellis, Ian O., Madhusudan, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528629/
https://ncbi.nlm.nih.gov/pubmed/24462520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.01.001
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