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Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15‐dependent drug resistance
The mitotic kinesin KIF11 (also called Eg5) plays critical roles in spindle functions. Although a number of small‐molecule inhibitors of KIF11 are currently in clinical development, drug‐resistance could be developed through compensation by another kinesin called KIF15. Using a newly developed infra...
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| Udgivet i: | Mol Oncol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528592/ https://ncbi.nlm.nih.gov/pubmed/24950801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.05.007 |
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