KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors

BACKGROUND: Malignant peripheral nerve sheath tumor (MPNST) constitutes the leading cause of neurofibromatosis type 1–related mortality. MPNSTs contain highly rearranged hyperploid genomes and exhibit a high division rate and aggressiveness. We have studied in vitro whether the mitotic kinesins KIF1...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Terribas, Ernest, Fernández, Marco, Mazuelas, Helena, Fernández-Rodríguez, Juana, Biayna, Josep, Blanco, Ignacio, Bernal, Gabriela, Ramos-Oliver, Irma, Thomas, Craig, Guha, Rajiv, Zhang, Xiaohu, Gel, Bernat, Romagosa, Cleofé, Ferrer, Marc, Lázaro, Conxi, Serra, Eduard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Supplement Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317059/
https://ncbi.nlm.nih.gov/pubmed/32642733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz061
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