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Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14
KIF14 is a mitotic kinesin whose malfunction is associated with cerebral and renal developmental defects and several cancers. Like other kinesins, KIF14 couples ATP hydrolysis and microtubule binding to the generation of mechanical work, but the coupling mechanism between these processes is still no...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8206134/ https://ncbi.nlm.nih.gov/pubmed/34131133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23581-3 |
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