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Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

DNA double strand breaks (DSBs) have detrimental effects on cell survival and genomic stability, and are related to cancer and other human diseases. In this study, we identified microtubule-depolymerizing kinesin Kif2C as a protein associated with DSB-mimicking DNA templates and known DSB repair pro...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhu, Songli, Paydar, Mohammadjavad, Wang, Feifei, Li, Yanqiu, Wang, Ling, Barrette, Benoit, Bessho, Tadayoshi, Kwok, Benjamin H, Peng, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012618/
https://ncbi.nlm.nih.gov/pubmed/31951198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53402
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