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Targeted tumor therapy by epidermal growth factor appended toxin and purified saponin: An evaluation of toxicity and therapeutic potential in syngeneic tumor bearing mice
Targeted toxin‐based therapeutics are hindered by poor intracellular uptake, limited stability and non‐specific immune stimulation. To address these problems, ligand‐targeted toxins in combination with low dose saponin mixtures have been adapted and tested in vivo in the past, however, undefined sap...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528469/ https://ncbi.nlm.nih.gov/pubmed/23298730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.12.004 |
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