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Targeted dianthin is a powerful toxin to treat pancreatic carcinoma when applied in combination with the glycosylated triterpene SO1861

Targeted cancer therapy provides the basis for the arrest of tumor growth in aggressive pancreatic carcinoma; however, a number of protein‐based targeted toxins lack efficacy due to insufficient endosomal escape after being endocytosed. Therefore, we tested a fusion protein of the ribosome‐inactivat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Bhargava, Cheenu, Dürkop, Horst, Zhao, Xiangli, Weng, Alexander, Melzig, Matthias F., Fuchs, Hendrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664001/
https://ncbi.nlm.nih.gov/pubmed/28755527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12115
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