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Reporter Assay for Endo/Lysosomal Escape of Toxin-Based Therapeutics
Protein-based therapeutics with cytosolic targets are capable of exhibiting their therapeutic effect once they have escaped from the endosomes or lysosomes. In this study, the reporters—horseradish peroxidase (HRP), Alexa Fluor 488 ((Alexa)) and ricin A-chain (RTA)—were investigated for their capaci...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052257/ https://ncbi.nlm.nih.gov/pubmed/24859158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6051644 |
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