The toxin component of targeted anti‐tumor toxins determines their efficacy increase by saponins

Tumor‐targeting protein toxins are composed of a toxic enzyme coupled to a specific cell binding domain that targets cancer‐associated antigens. The anti‐tumor treatment by targeted toxins is accompanied by dose‐limiting side effects. The future prospects of targeted toxins for therapeutic use in hu...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Weng, Alexander, Thakur, Mayank, Beceren-Braun, Figen, Bachran, Diana, Bachran, Christopher, Riese, Sebastian B., Jenett-Siems, Kristina, Gilabert-Oriol, Roger, Melzig, Matthias F., Fuchs, Hendrik
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528334/
https://ncbi.nlm.nih.gov/pubmed/22309811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.004
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