The toxin component of targeted anti‐tumor toxins determines their efficacy increase by saponins

Tumor‐targeting protein toxins are composed of a toxic enzyme coupled to a specific cell binding domain that targets cancer‐associated antigens. The anti‐tumor treatment by targeted toxins is accompanied by dose‐limiting side effects. The future prospects of targeted toxins for therapeutic use in hu...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Weng, Alexander, Thakur, Mayank, Beceren-Braun, Figen, Bachran, Diana, Bachran, Christopher, Riese, Sebastian B., Jenett-Siems, Kristina, Gilabert-Oriol, Roger, Melzig, Matthias F., Fuchs, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528334/
https://ncbi.nlm.nih.gov/pubmed/22309811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.01.004
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